Developing AdV vectors with their own modified genes and E1 and E3 replaced by foreign genes AdV5 with its own modified genes and E1 and E3 replaced by foreign genes in the E1 region AdV5 with its own modified genes and E1 and E3 replaced by foreign genes in the E3 region AdV5 with its own modified genes and E1 and E3 replaced by foreign genes in the E1 and E3 regions Non-AdV5 serotypes with their own modified genes and E1 and E3 replaced by foreign genes in the E1 region Non-AdV5 serotypes with their own modified genes and E1 and E3 replaced by foreign genes in the E3 region Non-AdV5 serotypes with their own modified genes and E1 and E3 replaced by foreign genes in the E1 and E3 regions